Freezing of gait in Parkinson's disease is related to impaired motor switching during stepping.
Identifieur interne : 000236 ( Main/Exploration ); précédent : 000235; suivant : 000237Freezing of gait in Parkinson's disease is related to impaired motor switching during stepping.
Auteurs : Katrijn Smulders [Pays-Bas] ; Rianne A. Esselink [Pays-Bas] ; Bastiaan R. Bloem [Pays-Bas] ; Roshan Cools [Pays-Bas]Source :
- Movement disorders : official journal of the Movement Disorder Society [ 1531-8257 ] ; 2015.
Abstract
Parkinson's disease (PD) has been associated with set switching difficulty in both the motor and the cognitive domain. However, the contribution of these set switching deficits to the primary motor symptoms of the disease is unclear. We investigated whether set switching deficits contribute to gait and stepping problems in PD. By contrasting motor and cognitive set switching within the same paradigm, we investigated the nature of set switching deficits associated with freezing of gait (FOG).
DOI: 10.1002/mds.26133
PubMed: 25641204
Affiliations:
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Bloem</name><affiliation wicri:level="3"><nlm:affiliation>Radboud University Medical Center, Donders Institute for Brain, Cognition and Behaviour; Department of Neurology, 6500, HB, Nijmegen, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Radboud University Medical Center, Donders Institute for Brain, Cognition and Behaviour; Department of Neurology, 6500, HB, Nijmegen</wicri:regionArea><placeName><settlement type="city">Nimègue</settlement><region type="province" nuts="2">Gueldre</region></placeName></affiliation></author><author><name sortKey="Cools, Roshan" sort="Cools, Roshan" uniqKey="Cools R" first="Roshan" last="Cools">Roshan Cools</name><affiliation wicri:level="3"><nlm:affiliation>Radboud University Medical Center; Donders Institute for Brain, Cognition and Behaviour; Department of Psychiatry, 6500, HB, Nijmegen, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Radboud University Medical Center; Donders Institute for Brain, Cognition and Behaviour; Department of Psychiatry, 6500, HB, Nijmegen</wicri:regionArea><placeName><settlement type="city">Nimègue</settlement><region type="province" nuts="2">Gueldre</region></placeName></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2015">2015</date><idno type="RBID">pubmed:25641204</idno><idno type="pmid">25641204</idno><idno type="doi">10.1002/mds.26133</idno><idno type="wicri:Area/PubMed/Corpus">000278</idno><idno type="wicri:Area/PubMed/Curation">000278</idno><idno type="wicri:Area/PubMed/Checkpoint">000236</idno><idno type="wicri:Area/Ncbi/Merge">004231</idno><idno type="wicri:Area/Ncbi/Curation">004231</idno><idno type="wicri:Area/Ncbi/Checkpoint">004231</idno><idno type="wicri:Area/Main/Merge">000236</idno><idno type="wicri:Area/Main/Curation">000236</idno><idno type="wicri:Area/Main/Exploration">000236</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Freezing of gait in Parkinson's disease is related to impaired motor switching during stepping.</title><author><name sortKey="Smulders, Katrijn" sort="Smulders, Katrijn" uniqKey="Smulders K" first="Katrijn" last="Smulders">Katrijn Smulders</name><affiliation wicri:level="3"><nlm:affiliation>Radboud University Medical Center, Donders Institute for Brain, Cognition and Behaviour; Department of Neurology, 6500, HB, Nijmegen, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Radboud University Medical Center, Donders Institute for Brain, Cognition and Behaviour; Department of Neurology, 6500, HB, Nijmegen</wicri:regionArea><placeName><settlement type="city">Nimègue</settlement><region type="province" nuts="2">Gueldre</region></placeName></affiliation></author><author><name sortKey="Esselink, Rianne A" sort="Esselink, Rianne A" uniqKey="Esselink R" first="Rianne A" last="Esselink">Rianne A. 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Bloem</name><affiliation wicri:level="3"><nlm:affiliation>Radboud University Medical Center, Donders Institute for Brain, Cognition and Behaviour; Department of Neurology, 6500, HB, Nijmegen, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Radboud University Medical Center, Donders Institute for Brain, Cognition and Behaviour; Department of Neurology, 6500, HB, Nijmegen</wicri:regionArea><placeName><settlement type="city">Nimègue</settlement><region type="province" nuts="2">Gueldre</region></placeName></affiliation></author><author><name sortKey="Cools, Roshan" sort="Cools, Roshan" uniqKey="Cools R" first="Roshan" last="Cools">Roshan Cools</name><affiliation wicri:level="3"><nlm:affiliation>Radboud University Medical Center; Donders Institute for Brain, Cognition and Behaviour; Department of Psychiatry, 6500, HB, Nijmegen, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Radboud University Medical Center; Donders Institute for Brain, Cognition and Behaviour; Department of Psychiatry, 6500, HB, Nijmegen</wicri:regionArea><placeName><settlement type="city">Nimègue</settlement><region type="province" nuts="2">Gueldre</region></placeName></affiliation></author></analytic><series><title level="j">Movement disorders : official journal of the Movement Disorder Society</title><idno type="eISSN">1531-8257</idno><imprint><date when="2015" type="published">2015</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Parkinson's disease (PD) has been associated with set switching difficulty in both the motor and the cognitive domain. However, the contribution of these set switching deficits to the primary motor symptoms of the disease is unclear. We investigated whether set switching deficits contribute to gait and stepping problems in PD. By contrasting motor and cognitive set switching within the same paradigm, we investigated the nature of set switching deficits associated with freezing of gait (FOG).</div></front></TEI><affiliations><list><country><li>Pays-Bas</li></country><region><li>Gueldre</li></region><settlement><li>Nimègue</li></settlement></list><tree><country name="Pays-Bas"><region name="Gueldre"><name sortKey="Smulders, Katrijn" sort="Smulders, Katrijn" uniqKey="Smulders K" first="Katrijn" last="Smulders">Katrijn Smulders</name></region><name sortKey="Bloem, Bastiaan R" sort="Bloem, Bastiaan R" uniqKey="Bloem B" first="Bastiaan R" last="Bloem">Bastiaan R. Bloem</name><name sortKey="Cools, Roshan" sort="Cools, Roshan" uniqKey="Cools R" first="Roshan" last="Cools">Roshan Cools</name><name sortKey="Esselink, Rianne A" sort="Esselink, Rianne A" uniqKey="Esselink R" first="Rianne A" last="Esselink">Rianne A. Esselink</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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